IBI/SHELTON SCIENTIFIC
230 LONG HILL CROSS RD
SHELTON, CT
06484
MANUFACTURER'S NAME:
IBI/SHELTON SCIENTIFIC
230 LONG HILL CROSS RD.
SHELTON, CT
06484
EMERGENCY TELEPHONE: TELEPHONE NUMBER FOR
(800) 451-8346 INFORMATION
(800) 253-4942 or (203) 929-8999
DATE PREPARED: 6-23-00
REVIEWED:
IDENTIFICATION
PRODUCT #: IB21040
NAME: DITHIOTHREITOL
CAS #: 27565-41-9
MF: C4H10O2S2
SYNONYMS
2, 3-BUTANEDIOL, 1, 4-DIMERCAPTO-, DL-THREO- * 2, 3-BUTANEDIOL, 1, 4- DIMERCAPTO-, (R*,
R*) - (+-) - (9CI) * CLELAND'S REAGENT * DL-THREO-1, 4-DIMERCAPTO-2, 3-BUTANEDIOL * (R*,
R*)- (+-) - 1, 4- DIMERCAPTO-2, 3-BUTANEDIOL * DITHIOTHREITOL * DL-DITHIOTHREITOL * DL-1,
4- DITHIOTHREITOL * RAC-DITHIOTHREITOL * DTT *
_____________________________TOXICITY HAZARDS______________________________
RTECS NO: X08576500
THREITOL, 1, 4-DITHIO-, DL-
TOXICITY DATA
IPR-MUS LD50: 169 MG/KG
JMCMAR 15, 600, 72
SCU-MUS LD50: 333 MG/KG
ARZNAD 22, 1434, 72
IVN-MUS LD50: 94 MG/KG
ARZNAD 22, 1434, 72
REVIEWS, STANDARDS AND REGULATIONS
NOES 1983: HZD X2950; NIS 1; TNF 35; NOS 3; TNE 627; TFE 436
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENTED
HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION.
____________________________HEALTH HAZARD DATA
__________________________
ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT.
EXPOSURE CAN CAUSE: NAUSEA, HEADACHE AND VOMITING
FIRST AID
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES.
IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF
BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING AND SHOES.
________________________________PHYSICAL DATA______________________________
MELTING PT: 42 C TO 44 C
APPEARANCE AND ODOR
WHITE POWDER
_______________________FIRE AND EXPLOSION HAZARD DATA___________________
FLASH POINT: >230 BY:
EXTINGUISHING MEDIA
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH
SKIN AND EYES.
USE WATER SPRAY TO COOL FIRE-EXPOSED CONTAINERS.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
_____REACTIVITY DATA__
INCOMPATIBILITIES
BASES
OXIDIZING AGENTS
REDUCING AGENTS
ALKALI METALS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
SULFUR OXIDES
HYDROGEN SULFIDE GAS
SPILL OR LEAK PROCEDURES
STEPS TO BE TAKEN IF MATERIAL IS RELEASED OR SPILLED
EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
WASTE DISPOSAL METHOD
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR
EQUIPPED WITH AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE, AND LOCAL LAWS.
]
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL -RESISTANT GLOVES, SAFETY
GOGGLES, OTHER PROTECTIVE CLOTHING.
USE ONLY IN A CHEMICAL FUME HOOD.
SAFETY SHOWER AND EYE BATH.
DO NOT BREATHE DUST.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
IRRITANT.
HARMFUL SOLID.
KEEP TIGHTLY CLOSED.
UNPLEASANT ODOR.
REFRIGERATE.
IRRITATING TO SKIN, EYES AND RESPIRATORY SYSTEM.
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL
ADVICE.
LABEL PRECAUTIONARY STATEMENT
IRRITANT
JUDGEMENTS AS TO THE SUITABILITY OF INFORMATION HEREIN FOR PURCHASER'S PURPOSES ARE
NECESSARILY THE PURCHASER'S RESPONSIBILITY. THEREFORE, ALTHOUGH REASONABLE CARE HAS BEEN
TAKEN IN THE PREPARATION OF SUCH INFORMATION, SHELTON SCIENTIFIC EXTENDS NO WARRANTIES,
MAKES NO REPRESENTATIONS AND ASSUMES NO RESPONSIBILITY AS TO THE ACCURACY OR SUITABILITY
OF SUCH INFORMATION FOR APPLICATION TO PURCHASER'S INTENDED PURPOSES OR FOR CONSEQUENCES
OF ITS USE.
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